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Frontier Interdisciplinary eXperiences (FIX) Coordinators for NCFPD Career Development Program

Principal Investigator: 
Justin Kastner; Jason Ackleson
The Frontier program and its flagship educational and mentorship effort the FIX program illustrate an inter-university approach to preparing undergraduate and graduate students for tomorrow's complex, multi-faceted Homeland Security challenges. Hallmarks of the FIX program include genuine...

Modification of Sample Preparation to Differentiate Live, Injured and Dead Bacteria in Polymerase Chain Reaction Assay

Principal Investigator: 
Teshome Yehualaeshet
Accurate determination of live, damaged or injured, and dead bacteria is important in microbiology detection to avoid false alarm. Dead bacteria present after processes such as pasteurization or disinfection might present no hazard but still can be detected by Polymerase chain reaction (PCR)...

On-Site Detection of Microbial Pathogens and Chemical Toxic Agents Using Novel Sensors Based on Quantum Dot Modified Molecular Imprinted Polymers

Principal Investigator: 
Keith Warriner
On-site diagnostic tools are an essential part of emergency management given that early detection of the hazard leads to rapid containment and corrective action. However, current diagnostic devices for on-site testing are lacking, expensive or require multiple step protocols and technical expertise...

Modular and Expandable Detection Platform for Current and Potential Food Toxins and Adulterants

Principal Investigator: 
Lawrence Wackett
This project is focused on developing a platform technology for detecting hundreds of potential toxins and adulterants in foods, including newly emerging threats to the food supply. The technology relies on the release of ammonia and is based on the action of specific enzymes acting on the toxin of...

Validation of Agent Inactivation and Isolation from Food Systems

Principal Investigator: 
Alvin Lee
Validation of a process needed to eliminate a microbiological or chemical hazard in food can be difficult. Processing technologies that have shown efficacy in eliminating a hazard under laboratory conditions, usually under well controlled parameters, may not be effective against the threat agent...

Validation and optimization of biologically modified electrically-active magnetic nanoparticles (nano-BEAMs) for direct capture and concentration of bioterrorism agents in various food matrices

Principal Investigator: 
Evangelyn Alocilja
The existing project focuses on the synthesis and novel application of biologically modified electrically-active magnetic nanoparticles (nano-BEAMs) for sample acquisition and pre-analytical processing to render representative samples of food products ready for rapid agent detection in multiple...

NCFPD Center of Excellence Food Protection Education Portal - Phase I

Principal Investigator: 
Craig Hedberg
There is a large and growing volume of food protection education and training material available to meet the increasing demand from government, industry, and public audiences. NCFPD can advance food protection education nation-wide by integrating resources from three projects, Food Protection...

Simultaneous detection of multiple food safety threat agents using multiplex PCR and PCR-based microarray approaches

Principal Investigator: 
Woubit Salah Abdela
Food-borne pathogens cause millions of clinical illnesses every year and cost billions of dollars to manage and control. Several recent examples including Salmonella enterica serovar Saintpaul in produce, Escherichia coli O157:H7 in ground beef, Listeria monocytogenes in ready to eat meat have led...

Proof-of-concept study for the development of a cell-free GPCR-based biosensor for rapid non-specific detection of chemical and biological toxic agents

Principal Investigator: 
Evangelyn Alocilja
This project is a high-risk/high-reward exploratory proof-of-concept work to evaluate the potential of G-protein coupled receptors (GPCRs) as sensing elements in biosensor devices for rapid non-specific but highly sensitive detection (detect-to-warn) of toxicants in selected complex food matrices...

Melamine-Cyanuric Acid Detection System for Purposely Adulterated Foods

Principal Investigator: 
Lawrence Wackett
Melamine (2,4,6-triamino-1,3,5-triazine) has been used on numerous occasions by individuals as a food adulterant to boost the apparent nitrogen content of food. Together with cyanuric acid, melamine causes acute kidney failure. In the recent infant formula incident, 150,000 children were...

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