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Biological Threats and Countermeasures

Inactivation of Microbial Agents with High Concentrations of Industrial Sanitizers

Principal Investigator: 
Katherine Swanson
This study evaluated the effectiveness of currently available chemical biocides against Bacillus anthracis spores and Yersinia pseudotuberculosis (as a surrogate for Y. pestis) on clean and soiled stainless steel surfaces. Information on the effect of available biocides on the above organisms is...

FASTMAN Integrated Device for Detection of Select Agents

Principal Investigator: 
Vivek Kapur
Our long-term goal is to develop assays for the sensitive, specific, and reliable detection of select agents in the food supply at the field, processing plant, distribution system, or at point-of-sale/use. Our immediate objectives have been to develop and validate accurate and convenient analytic...

Toxin/Pathogen Inactivation and Disposal of Intentionally Contaminated Foods

Principal Investigator: 
Craig Benson
Information is currently lacking regarding methods to safely dispose of food, packaging, and related materials contaminated with a variety of pathogenic or toxic agents. One of the goals of this oneyear pilot project is to document the state of knowledge concerning microorganisms and toxins...

A Systematic Approach for the Detection of Bioterrorism Agents in Complex Sample Matrices

Principal Investigator: 
Lee Ann Jaykus
The purpose of this project was to develop selective ligands (peptide and nucleic acid) to facilitate pre-analytical capture and subsequent detection of priority pathogens and bioagents (ricin B chain and B. anthracis spores) in foods. Twenty peptides displaying affinity to ricin B chain have been...

Determination of Y. pseudotuberculosis Survival in Milk under Temperature Stresses

Principal Investigator: 
Teshome Yehualaeshet
Based on the potential for intentional use of Yersinia to contaminate the food supply and its ability to grow even in refrigerated foods, this study focuses on developing a protocol for extracting PCRcompatible genomic DNA from the surrogate Y. pseudotuberculosis in spiked milk and to determine the...

Conversion of Curriculum for Food Safety and Food Defense Certificate from In-Class Delivery to Distance Learning Format

Principal Investigator: 
Craig Hedberg
The overall goal of this project is to make educational programs for Food Defense more widely available to health professionals, food regulatory officials and food defense specialists in industry. Our objective is to convert the food defense courses currently offered through the PHI into a distance...

A Probabilistic and Cost-Based Index of Food Threats

Principal Investigator: 
Hamid Mohtadi
This project develops a data-based probabilistic algorithm for food vulnerabilities and applies those probabilities to estimate the expected costs (losses) both in the market (loss of sales) and in health care. This will enable policy makers and food companies to prioritize and rationalize the...

Diagnostic Tools and Gap Analysis for Food Firms' Defense Practices

Principal Investigator: 
Jean Kinsey
1. To refine and test the Diagnostic Tool for Food Defense, a deliverable product from the Supply Chain Benchmarking Project. 2. To have several food companies using the Diagnostic Tool and participating in the practices that will make their companies and the food they handle safer and enable them...


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